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Check Intently (one)pentobarbital will lessen the extent or result of mifepristone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe. CYP3A4 inducers have not been analyzed, coadministration not suggested by producerSodium valproate and valproic acid look to lessen barbiturate metabolism; thus, barbiturate blood amount